Articles Tagged With: brain
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Cognitive-Motor Dissociation in Patients Admitted to ICUs After Acute Brain Injuries
In a large, prospective, single-center study, more than one in six patients with acute brain injuries may have cognitive-motor dissociation (CMD) (e.g., they harbor capacity to modulate their brain activity in response to motor commands while remaining behaviorally unresponsive at the bedside). Some acute CMD patients were found to have a much higher chance for recovery of neurological functions and for reaching independent levels of activities of daily living by 12 months after brain injury.
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Measurement of Brain Vital Signs in Concussed Athletes
These investigators prospectively studied auditory event-related potentials (ERPs) in junior competitive male ice hockey players and identified a pattern of ERPs that distinguishes acutely concussed from non-concussed players, establishing this noninvasive, easy-to-administer test as a biomarker to assist trainers, coaches, and clinicians with making the diagnosis of concussion.
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Stroke: The Subtle, Atypical, and Enigmatic
This article will explore the subtle and enigmatic presentations of stroke. These patients often will present with nonspecific symptoms, such as vision problems, headache, a subtle language deficit, dizziness, or amnesia.
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Are Women More Prone to Brain Injury Than Men When Playing Soccer?
Repeated subconcussive injuries to the brain, such as “heading” the ball in soccer, result in more severe injury and slower recovery in women compared to men.
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Hypercapnic Acidosis and Clinical Outcomes in Patients With Acute Brain Injury
In this multicenter retrospective study, hypercapnic acidosis was associated with worse clinical outcomes in mechanically ventilated patients with acute brain injury.
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Ufmylation and Brain Development: Effects of Gene Mutations
Genetic mutations that can modify post-translational proteins and their interactions may result in serious developmental disorders of the brain. Ufmylation is such a process, and mutations in the genes that regulate this process may have profound effects on the developing brain.
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Intracranial Pressure Changes in Mild Traumatic Brain Injury
After an exhaustive review of the animal and human studies literature regarding mild traumatic brain injury (mTBI), Haider et al. did not reach consistent conclusions regarding evidence for intracranial pressure elevation in human patients who sustain an mTBI.
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Brain Imaging and Alzheimer’s Risk: Valid Surrogates or Just Pretty Pictures?
In an observational multimodality brain imaging study, investigators found sex and age differences correlated with endophenotypes of late-onset Alzheimer’s disease.
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Optimizing Brain Oxygen in Severe Traumatic Brain Injury
In a Phase II, single-blind, randomized, multicenter trial, the use of intraparenchymal brain tissue oxygenation monitoring reduced brain tissue hypoxia in patients with severe traumatic brain injury.
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Pitfalls in the Treatment of Seizures Associated With Brain Tumors
In this multicenter, observational study, the authors assessed the prevalence of neuropsychiatric side effects from medications in subjects with tumor-related epilepsy. Levetiracetam was found to have the highest prevalence of such side effects.