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This systematic review and meta-analysis demonstrates that oral decontamination with antiseptic preparations decreases the risk of ventilator-associated pneumonia but has no effect on mortality, duration of mechanical ventilation or length of stay in the ICU.
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Many nursing home patients are admitted with prescriptions for proton pump inhibitors or H2-receptor antagonists without any obvious indication.
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This study of oral versus intravenous prednisolone in patients hospitalized with exacerbations of COPD showed no differences in any outcome variable between the two forms of administration.
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RCVS occurs in a variety of clinical settings, and should be considered and investigated in any person with sudden severe headache that is unexplained by other disorders.
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This retrospective analysis of data on patients with acute lung injury shows that transfusion of red blood cells in such patients is associated with increased in-hospital mortality, and that the risk is highest with transfusion of non-leukoreduced blood and transfusion following the onset of acute lung injury.
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In this issue: Stop smoking drug Chantix rates stronger warning from FDA; Type 2 diabetes surgery on the way?; Vytorin study inconclusive; Influenza A virus found resistant to Tamiflu; FDA actions.
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The Timing Hypothesis argues that estrogen can reduce the risk of coronary heart disease when administered to relatively young postmenopausal women before atherosclerosis has developed to the stage of unstable plaques (plaques with necrosis and inflammation).