Articles Tagged With:
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Lack of Trust and Knowledge Hinders Genetic Research Recruitment
Try using lay language to better explain genetic research as part of the informed consent process. Addressing participants’ concerns carefully may help gain participants’ trust in research, and thus improve recruitment of diverse patient populations.
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Patient or Family May Need Translator During Ethics Consult
A good rule of thumb is to stop and check for comprehension after sharing a key point, especially when that point will influence decision-making or may change an individual’s perspective on the situation.
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When Surrogate Decision-Makers Misunderstand Patients’ Condition
In the view of clinicians, surrogates of patients with higher acuity of illness could better understand the clinical situation. However, those surrogates might be less likely to correctly identify all the affected organ systems. Surrogates who seem to strongly grasp the situation may not actually feel as secure in their understanding.
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Conflicts of Interest Are Prevalent in Clinical Guidelines
Even the appearance of bias in clinical practice guidelines is problematic, since it could diminish public trust in medicine. Ensuring there are functioning systems in place to keep practice guidelines objective and free of this influence must be a priority.
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Early, Integrated Education May Prevent ‘Ethical Erosion’
Modalities such as ethics rounds or shadowing could help make these considerations a part of everyday practice.
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Many Ethics Committees Are Not Following AAP Guidance
In a survey of ethics consultant leaders at children’s hospitals, researchers found multiple practice gaps, including training needs; informing staff, patients, and family about ethics services; and scope of ethics service. These practice gaps could erode ethics quality and narrow ethics reach.
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New Ethical Guidance on Pediatric Decision-Making
According to the recommendations, ethical decision-making can factor in parents’ consideration of the child’s non-health interests (e.g., a child’s interest in playing football, even if it risks concussions), and also may consider the interests of other family members, provided those do not severely compromise the child’s health.
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Canakinumab Injection (Ilaris)
Canakinumab can be prescribed to adults with gout in whom nonsteroidal anti-inflammatory drugs and colchicine are contraindicated, are not tolerated, or do not provide an adequate response, and in whom repeated courses of corticosteroids are not appropriate.
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An RNA Shot for Hypertension?
One dose of a new RNA-based drug administered by subcutaneous injection, which blocks hepatic angiotensinogen production, resulted in sustained reductions in blood pressure in patients with hypertension for up to 24 weeks without any serious adverse effects.
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Is the Combination of a GLP-1 Agonist and a SGLT2 Inhibitor Safe?
An analysis of the Harmony Outcomes study and a meta-analysis combining it with the AMPLITUDE-O study of the addition of a glucagon-like peptide 1 receptor agonist (GLP-1 RA) in a subgroup of type 2 diabetes patients on baseline sodium-glucose cotransporter-2 (SGLT2) inhibitor therapy has shown that major adverse cardiovascular events are reduced by GLP-1 RA, regardless of baseline SGLT2 use, and there was no difference in serious adverse events.