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Early seizures and EEG abnormalities as well as status epilepticus predicts worse outcome in SCN1A-positve Dravet syndrome in this new, large cohort of patients.
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Dementia and benzodiazepines; effectiveness of omega-3 fatty acid and Ginkgo biloba supplements; and FDA actions.
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Up to 50% of patients with seronegative ocular myasthenia gravis have antibodies to clustered acetylcholine receptor antibodies that can fix complement and passively transfer disease to experimental mice.
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Multiple sclerosis (MS) relapse rates were found to increase post in vitro fertilization (IVF) in a small population of MS patients. The risk for relapse was highest in the first 3 months post-IVF.
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Three common medications amitriptyline, duloxetine, and pregabalin all appear equally efficacious in treating neuropathic pain from diabetic neuropathy.
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Side effects of statins; effects of cannabis use; antihypertensives and lip cancer; and FDA actions.
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This case series of patients with painful legs and moving toes is the largest to date and describes association with female gender, peripheral neuropathy and radiculopathy, cancer, and autoimmune disorders. Neurophysiology suggests an additional central component, supporting recruitment of a spinal cord or brainstem generator.
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Biomarkers in the cerebrospinal fluid open the possibility of diagnosing early or even presymptomatic cases of Alzheimer's disease, thereby expanding the potential window for therapy.