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It would be reasonable to empirically try sildeanfil and related drugs in both men and women with MS having sexual complaints.
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The availability of sensitive and reproducible measures of autonomic function has improved physicians’ ability to diagnose these disorders.
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The only consistent intervention which appears to extend lifespan in mammals has been caloric restriction. This has been shown in a number of species, and there are ongoing studies in primates. Patients who voluntarily undergo caloric restriction show improvement in some of the biomarkers which improve in calorically restricted mammals. Other interventions, however, have been largely unsuccessful in extending lifespan.
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Patients with spinal epidural abscess may be normothermic and have normal WBC counts. Urgent surgery was more likely to be offered to patients presenting with neurologic deficits than with pain alone. Patients treated without early surgery were significantly more likely to deteriorate and suffer poor outcomes.
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It is recognized that most cases of chronic tinnitus are generated by central brain mechanisms that may be amenable to treatment with cognitive therapies and magnetic stimulation protocols of the temporal and frontal lobes.
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Normal pressure hydrocephalus remains a clinical diagnosis and standardized clinical assessments predict a positive response to shunting in most patients.
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Azithromycin and cardiac risk; warfarin and heart failure; aspirin and VTE; effectiveness of long-acting contraceptives; and FDA actions.
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Changes in CSF metabolites reflect dopamine and norepinephrine deficiency in Parkinson's disease, and may be sensitive in early identification.
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Over a 6-year period, 2305 patients with reduced left ventricular ejection fraction and normal sinus rhythm were randomized to warfarin treatment (target INR of 2.0 to 3.5) or aspirin (325 mg per day) and followed to determine the rate of a composite endpoint of ischemic stroke, intracerebral hemorrhage, or death from any cause.