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The DANAMI-2 investigators, representing 29 hospitals and a patient base reflecting 62% of the Danish population, have reported on a trial assessing whether randomization to either fibrinolytic therapy or transport to an interventional facility results in differing major cardiovascular rates following acute ST elevation myocardial infarction (STEMI).
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Stroke with no determined cause, or cryptogenic stroke (CS), accounts for nearly 40% of all ischemic strokes. Traditionally, it has been held that CS carries a more benign prognosis than other stroke subtypes. However, until this recent study, the long-term risk of recurrent stroke in this large segment of the stroke population had never been prospectively studied.
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This study suggests that the risk conferred by an inherited thrombophilia for ischemic stroke is likely to be low overall and almost nonexistent in some ethnic groups such as individuals of African or African-Caribbean descent.
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Genetic investigations have made considerable progress in identifying mutations associated with familial amyotrophic lateral sclerosis (ALS). The identification of genetic alterations in patients with sporadic ALS, however, has lagged behind. The present study is a major advance in investigating the etiology of ALS.
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The FDA has approved vardenafil (LevitraBayer and GlaxoSmithKline) for the treatment of erectile dysfunction in men. Vardenafil joins sildenafil (Viagra) as the only 2 drugs approved for this indication in this country.
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Perhaps the most intriguing aspect of the severe acute respiratory syndrome (SARS) epidemic was its patterns of spread. Sometimes, few people became infected, despite exposure. In other cases, dozens of people became ill.
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In the past outbreak of severe acute respiratory syndrome (SARS), some visitors, patients, and employees were exposed to the virus before anyone was aware that another patient or visitor was infected.
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Health care workers with pneumonia may be the sentinels for a new outbreak of severe acute respiratory syndrome (SARS). Faced with the dilemma of identifying the first suspected cases of SARS amid a backdrop of widespread, seasonal respiratory illness, public health authorities are urging hospitals to monitor their employees health.
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Intraperitoneal chromic phosphate did not decrease the risk of relapse or improve survival for patients with stage III epithelial ovarian cancer after a negative second-look surgery.
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Combining capecitabine and oxaliplatin yields promising activity in advanced colorectal cancer; therefore, the capecitabine dose we used is probably too high. The main toxicity is diarrhea, which is manageable with appropriate dose reductions.