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A new, and as of yet unpublished study, has raised increased concern about the relationship between rofecoxib (Vioxx), Mercks blockbuster COX-2 inhibitor, and cardiovascular events. The study, which was presented at a meeting in Bordeaux France, was financed by the FDA in collaboration with Californias HMO giant Kaiser Permanente.
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Issues July, August, and September 2004 were printed as Volume 21. They should read Volume 23.
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A calcium score < 100 eliminates the need for myocardial perfusion scans (MPS), but patients with a negative MPS often have coronary calcium. These findings imply a potential role for applying coronary artery calcium screening after MPS among patients manifesting normal MPS.
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The use of automatic external defibrillators by trained volunteers is safe and effective, particularly in public locations where there is at least a moderate likelihood that an out-of-hospital cardiac arrest will be witnessed.
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The developing world is experiencing an epidemic of CAD which expects to continue to increase in the foreseeable future.
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Low-dose aspirin is as effective as warfarin for preventing cerebral thromboembolic events after bioprosthetic aortic valve replacement.
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The Prevention of Atrial Fibrillation After Cardioversion Trial was a placebo-controlled study comparing sotalol and a quinidine/verapamil combination in patients with persistent atrial fibrillation after cardioversion.
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In the United States, its a case for the courts when an HIV-infected mother wishes to breast-feed. In most of the nations where HIV proliferates, women are faced with a Sophies choice: Should they breast-feed and risk transmitting HIV to their infant, or should they use substitute nutrition, which may place their infant at greater risk of dying within the first year?
