Articles Tagged With:
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IRBs Determine Acceptable Risk for Pediatric Studies
IRBs may be disinclined to approve study protocols based on the mistaken belief there is little public support for net-risk pediatric research. Thus, researchers should show IRBs data on the risks of the interventions in question. To demonstrate the study’s social value, researchers could explain how the approach under investigation could help address an important health condition.
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Researchers Encounter Challenges with Study Development Protocols
Tutorial videos and webinars, in-person training, and sample forms are some of the ways researchers try to keep up with IRB protocols to prevent any study delays.
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Unique Ethical Issues with Research on Difficult-to-Treat Depression
Researchers should focus on these three areas: How to define this group of patients, which is heterogenous; how to acquire and interpret clinically meaningful outcome metrics; and how to design clinical trials to promote generalizability.
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Are Neurotechnology Tools Designed Ethically? Public Is Skeptical
Industry members cannot just assume people trust them to design devices ethically. Marketing campaigns and advertisements are one way to spread the message. But even more fundamental is incorporating patient and end user feedback in the design process.
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Citizen Science Projects Surging, But Often Lack IRB Ethical Oversight
Failure to return results, exploitation of participants, poor quality data, and power imbalance are top ethical worries. Citizen scientists should pay attention to issues of power and exploitation, and think about what processes to use to stay ahead of those concerns.
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Diagnosing and Managing Pediatric Foreign Body Ingestions: Part II
The process of diagnosing and managing foreign bodies has changed over the last few years. In Part II, the authors discuss not only the process for managing the majority of foreign bodies, but also unique ingestions that require special care.
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Glycemic Control During Labor in Women with Diabetes
This study demonstrated an increased risk of neonatal hypoglycemia in neonates born to patients with diabetes as the result of maternal hyperglycemia in labor. However, strict intrapartum maternal glycemic control appeared to be associated with a reduced risk of neonatal hypoglycemia only in patients with gestational diabetes on medication, but not for other diabetes subtypes.
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Oral vs. IV Iron for the Treatment of Iron-Deficiency Anemia in Pregnant Women
Compared to oral iron, intravenous iron reduced maternal anemia at delivery (40% vs. 85%, P = 0.039), and rates of maternal hemoglobin < 10 g/dL were lower with intravenous iron compared to oral iron (10% vs. 54%, P = 0.029). Rates of mild to moderate adverse events were similar between the two groups, and no severe adverse reactions were noted with intravenous iron.
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The Pseudogestational Sac of Ectopic Pregnancy: Does it Really Matter?
In this retrospective cohort study of 1,236 women, the rate (2.2%) of ectopic pregnancy was rare among women with a fluid collection (or pseudosac) in the uterus. The size of the fluid collection was not predictive of ectopic pregnancy. The presence of an intrauterine fluid collection decreased the risk of ectopic pregnancy (adjusted relative risk, 0.09; 95% confidence interval, 0.05-0.19) after adjusting for age and the presence of bleeding.
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Is the Timing of Interval Postpartum Insertion of Intrauterine Device Associated with the Frequency of Complications?
Having an intrauterine device (IUD) inserted at four to eight weeks postpartum was associated with higher frequency of uterine perforation, but not higher frequency of expulsion, compared to IUD insertion at nine to 36 weeks postpartum. Overall, perforation and expulsion rates were low.