Articles Tagged With:
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Immunosuppressants and the Risk for Clostridioides difficile Infection
A retrospective cohort study found that for patients taking immunosuppressing medications, the greatest risk for C. difficile infection occurred for those receiving calcineurin inhibitors and those taking drugs from multiple immunosuppressant classes.
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Aminoglycoside-Induced Ototoxicity: Test Before You Treat?
Mitochondrially inherited, aminoglycoside-induced ototoxicity can cause irreversible hearing loss. Approximately 0.2% of the population is at risk, and new point-of-care genetic testing could prompt avoidance of aminoglycoside use without undue delay in antibiotic administration.
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Midlines vs. Peripherally Inserted Central Venous Catheters
Midline catheters are, at a minimum, at least as safe or safer than peripherally inserted central catheters for durations of at least 14 days, thus offering an effective alternative for venous access.
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Waning Pandemic May Mean Less Interest in Advance Care Planning
National Healthcare Decisions Day is a time for Americans to document wishes for end-of-life care.
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COVID-19 Associated with Significant Increase in Hospital-Acquired Bloodstream Infections
The time period of the COVID-19 pandemic was associated with increases in hospital-onset bloodstream infections, mainly in patients with COVID-19.
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Ketamine vs. Etomidate for Emergency Intubation
In a single-center, open label study, ketamine for emergency intubation compared to etomidate was associated with lower seven-day mortality, although 28-day mortality was similar.
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Awake Prone Positioning for COVID-19-Related Acute Hypoxemic Respiratory Failure
This special feature summarizes the literature associated with awake prone positioning (APP), describes known factors related to successful APP, and highlights current recommendations regarding APP in the setting of COVID-19.
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Informed Consent Considerations if Surgeon Delegates Portion of Operation
Surgeons should be clear there will be other providers in the OR, and that some elements of the operation — not the critical portion the attending has to manage, but other elements — can be delegated to a qualified member of the surgical team. However, the primary attending surgeon’s personal responsibility for the safety and the welfare of the patient cannot be delegated.
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New Guidance to Promote Diverse Populations in Cardiovascular Trials
Individuals who participate in randomized clinical trials should be representative of the patients who will be treated with the drugs under investigation. Unfortunately, studies have consistently shown women and those from racial and ethnic minority groups are consistently underenrolled in cardiovascular clinical trials relative to their disease burden in the population.
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Investigators Make Ethical Commitment for Neuroscience Research in Humans
There are overarching principles of ethical conduct of human neuroscience research, but the methods and implementations may vary across institutions.