Articles Tagged With:
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Brain Iron Chelation with Deferiprone in Parkinson’s Disease
In a randomized, placebo-controlled treatment trial, deferiprone administered to early, levodopa-naive Parkinson’s disease patients over 36 weeks was associated with worsening of their symptoms, in spite of imaging evidence for reduction of iron in the substantia nigra.
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Body Weight Decline in Cognitively Intact Older Adults May Predict Future Cognitive Impairment
Among cognitively intact individuals, those who develop mild cognitive impairment (MCI) had faster body mass index (BMI) decline and significantly lower BMI seven years before MCI diagnosis. However, after MCI diagnosis, there was no difference in BMI decline between patients who developed dementia and those who did not.
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What Is Oculopharyngodistal Myopathy?
Distal limb myopathies are rare disorders and are difficult to diagnose. Current muscle biopsy technology, coupled with genetic analysis, offers the best hope for an accurate diagnosis of these unusual neuromuscular disorders. Unfortunately, treatments remain elusive.
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Misdiagnosis of Autoimmune Encephalitis
A recent multicenter, retrospective review of 393 adult patients given a diagnosis of autoimmune encephalitis noted that 107 patients (27%) were misdiagnosed and ultimately had other diagnoses confirmed, but after a considerable delay.
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Long-Term Statin Use Associated with Lower Stroke Risk
A cohort of Danish patients who were taking the cholesterol control medication were less likely to experience an intracerebral hemorrhage.
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Patients with Solid Tumors Admitted with Septic Shock: Outcomes and Mortality Predictors
The presence of metastatic disease, respiratory failure, elevated lactate levels, and poor prior performance scores were independent predictors of mortality in patients with solid tumors admitted with septic shock.
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Does Surviving an ECMO Stay Put Patients at Greater Risk for Mental Health Problems?
Survivors of extracorporeal membrane oxygenation (ECMO) have a modest increase in risk of new mental health diagnoses after discharge compared with intensive care unit survivors who do not undergo ECMO.
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Does Selective Decontamination of the Digestive Tract Reduce In-Hospital Mortality in Critically Ill Adults?
The SuDDICU randomized controlled trial of Australian patients found that selective decontamination of the digestive tract (SDD) did not significantly decrease in-hospital mortality, although the confidence interval around the effect estimate includes a clinically important benefit. In a separate systematic review and meta-analysis that included 32 randomized trials and 24,389 participants, SDD was associated with reduced hospital mortality compared with standard care.
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2022-2023: A Severe Season for Respiratory Syncytial Virus
The 2022-2023 northern hemisphere respiratory syncytial virus (RSV) season began with fury, crowding hospitals and making many young children extremely ill. Meanwhile, advancing research points to potential means of better preventing RSV infection.
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Viral Swarm: ‘Tripledemic’ Pushes Healthcare Facilities to the Brink
Respiratory infections are causing hospitalizations and deaths nationally in an unprecedented trifecta of influenza, respiratory syncytial virus, and COVID-19.