Articles Tagged With:
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Ethical Oversight of Chimeric Research
A key concern is whether evidence will emerge indicating significant functional changes in the cognition and behavior of nonhuman animals that contain human cells. If so, it may be difficult to resolve ethical issues regarding the moral status of those chimeric animals.
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Informed Consent Is Central Ethical Issue for Studies of Pig Organ Transplants
Existing policies for human research subject protection might not be adequate for these trials, mainly because there are so many unknowns with outcomes in humans.
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IRBs Likely Need Outside Expertise When Reviewing Xenotransplantation Study Protocols
An enthusiastic surgeon who wants to initiate a clinical trial for xenotransplantation may, in their enthusiasm, minimize the potential problems to the IRB. The surgeon might win approval, but the IRB might lack the expertise to know if they are receiving all the facts.
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For Researchers Using Social Media Data, Consent Is Ethical Worry
Researchers struggle with the ethical implications of sharing information that enables Twitter users to be identified. More guidance is needed from IRBs, as there does not seem to be a consensus on best practice in terms of research ethics.
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Study: New Physicians Develop Financial Ties Quickly
Earlier recognition and intervention during graduate medical education to improve professionalism and systems-based practice skills may limit future conflicts of interest with industry.
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Low-Fat vs. Mediterranean Diet for Secondary Prevention
A study of stable coronary heart disease patients comparing the Mediterranean diet to a low-fat diet over a seven-year follow-up showed the Mediterranean diet was superior at preventing major cardiovascular events.
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Is It Better to Up-Titrate Medications Faster in Acute Heart Failure Patients?
Early intensive up-titration of guideline-recommended therapy in patients admitted for heart failure reduced 180-day readmission and all-cause mortality rates at the cost of more adverse events (but not serious or fatal ones).
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New Therapy for Resistant Hypertension
Aprocitentan demonstrated efficacy for additional therapy beyond standard multidrug treatment in resistant hypertension.
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Current and Future Options for Male Contraception
The following is a summary of the existing male contraceptive options and an overview of future ones.
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Tocilizumab Injection (Actemra)
The FDA has approved tocilizumab injection to treat COVID-19 among hospitalized adult patients who are receiving systemic corticosteroids and require supplemental oxygen.