Articles Tagged With: Cholesterol
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Long-Term Statin Use Associated with Lower Stroke Risk
A cohort of Danish patients who were taking the cholesterol control medication were less likely to experience an intracerebral hemorrhage.
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Triglyceride-Lowering Therapy and Cardiovascular Events
Researchers studied pemafibrate vs. placebo in patients with type 2 diabetes, mild-to-moderate triglyceride elevations, and low levels of HDL and well-controlled LDL cholesterol. Despite a 31% reduction in triglyceride levels, there was no improvement in the risk of cardiovascular outcomes over a median follow-up of 3.4 years.
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Statins Plus Ezetimibe vs. Statins Alone
A comparison of rosuvastatin 10 mg/day plus ezetimibe (10 mg/day) to 20 mg/day of rosuvastatin alone showed non-inferiority in three-year major cardiovascular outcomes, with lower LDL cholesterol levels and fewer episodes of drug discontinuation or dose reductions in the combination therapy group.
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Secondary Prevention Statin Adherence and Major Adverse Cardiovascular Events
A study of adherence to statin therapy after an atherosclerotic cardiovascular event demonstrated full adherence for five years was associated with significantly lower major adverse cardiovascular events, although only 5% of these patients achieved full compliance for five years.
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Inclisiran Injection (Leqvio)
Inclisiran can be prescribed as an adjunct to diet and maximally tolerated statin therapy for adults with heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease who required additional low-density lipoprotein cholesterol lowering.
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Researchers Observe No Connections Between Statin Therapy, Cognitive Decline
But randomized trials are needed to better detail long-term risk-benefit ratio. -
Another Agent for Hypercholesterolemia
A pooled analysis of three randomized, controlled trials of inclisiran in patients with atherosclerotic cardiovascular disease or its risk equivalent showed impressive reductions in LDL cholesterol with subcutaneous injections every six months.
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Importance of Atherosclerotic Disease Risk Factors in Myocardial Infarction Patients
ST-elevation myocardial infarction patients without standard risk factors recorded a higher all-cause mortality rate that was particularly evident in women. Using proper therapy in these patients may attenuate this risk.
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What Causes Stroke in Young Patients?
A patient might be young, but he or she could be living with serious, unaddressed medical conditions that can lead to disaster.
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Evinacumab-dgnb Injection (Evkeeza)
Evinacumab-dgnb should be prescribed as an adjunct to other low-density lipoprotein cholesterol-lowering therapy to treat patients age 12 years and older with homozygous familial hypercholesterolemia.