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Breast cancer in young women is uncommon, but when it does occur, it is thought to be very aggressive. In this large series of young (< 35 years old) patients from a single institution seen over a 13-year period, high tumor grade, hormone receptor negativity, and family history of ovarian cancer turned out to be significant negative prognostic indicators.
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Stopping Aspirin Before Surgery; The Sponge Returns; Preventing Metabolic Syndrome; FDA Actions.
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The well-known mantra of primary ovarian cancer management is surgery. The procedure has modified little in the last 30 years as the goal in advanced cases has been cytoreduction and, in seemingly early cases, it has been accurate staging.
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Reproducibility of complex proteomic signatures in detecting early stage ovarian cancer has proven to be a significant challenge in the field of biomarker discovery. Although early reports of proteomic profiling demonstrated near 100% sensitivity and specificity in discriminating ovarian cancer from non-cancer, the ability to reproduce these results across datasets has been difficult.
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Laparoscopic surgery is rapidly becoming more commonly used for colorectal cancer resection. The current study reports the short-term findings of a relatively large, randomly assigned comparison of laparoscopic surgery vs standard open procedure for patients with newly diagnosed colon or rectal cancer.
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The Glasgow Prognostic Score (GPS) is an easily derived measure of underlying inflammatory processes. In this series of 101 patients with newly diagnosed advanced non-small cell lung carcinoma, it proved superior to the ECOG Performance Scale in predicting survival. After initial treatment, however, the prognostic value fell, but this may have been the result of fewer evaluable patients at the latter time points.
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A 62-year-old Caucasian woman returns to her primary care physician for a follow-up visit after routine colonoscopy and is accompanied by her 63-year-old husband. The gastroenterologist had resected three adenomatous polyps and suggested a repeat colonoscopy in 1 year.
