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A 84-year-old retired professor was referred for second opinion regarding management of prostate cancer. He had been relatively healthy, with a history of hyperlipidemia and gout.
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The occurrence of skin rash in patients receiving cetuximab is common, and for patients with colon cancer, this has been associated with better clinical outcomes.
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Very limited data are available on autologous transplant outcomes for uncommon or rare multiple myeloma (MM) subtypes.
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With the development of an increased understanding of cellular biology, in general, and the regulation of eosinophils, in particular, the heterogeneous diagnosis of hypereosinophilic Syndrome (HES) has now been better defined and a classification system has been developed with clear clinical implications.
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Statins and liver function; dosing timing for thyroxine; rivaroxaban for VTE, DVT, and stroke; echinacea and the common cold; and FDA actions.
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A 58-year-old retired school principal was seen in the office because of malaise and weight loss. He had been well until 4 years ago when he was discovered, at a routine annual exam, to have lymphocytosis.
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In a retrospective review of consecutive patients with colon cancer, the presence of diabetes mellitus was found to confer negative prognostic information with regard to overall, and cancer-specific, survival. Notably, it was in patients with stage II disease that the presence of diabetes was of most importance.
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A trial undertaken by EORTC was designed to determine if neoadjuvant chemotherapy would be successful in the absence of post-surgical chemotherapy in enhancing overall survival in patients with locally advanced gastric cancer. The trial did not accrue sufficient numbers of patients to demonstrate a survival benefit. However, presurgical chemotherapy was associated with a higher rate of complete resection and fewer positive lymph nodes, features that suggest progression-free and overall survival might be favorably affected.
