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Studies demonstrate that angiotensin-converting-enzyme (ACE) inhibitors such as captopril reduce mortality and cardiovascular morbidity for patients with myocardial infarction (MI) complicated by left ventricular systolic dysfunction, heart failure, or both. The authors surmised that since angiotensin II can be generated despite ACE inhibition, further efficacy can be obtained if receptor antagonists are combined with ACE inhibitors.
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Trauma to the thoracic cavity is responsible for approximately 10-25%
of all trauma-related deaths, with the majority of these deaths
occurring after arrival at the emergency department. The mortality for
isolated chest injury is relatively low (less than 5%); however, with
multiple organ system involvement, the mortality approaches 30%. This
article dissects the critical aspects of thoracic trauma and highlights
acute care management strategies.
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Changes in screening, endocervical sampling, nomenclature, and improvements in treatment likely explain the increased in situ cervical SCC incidence in white women and black women. Increasing AIS incidence over the past 20 years in white women has not yet translated into a decrease in invasive AC incidence.
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Survival rates were similar in patients with advanced-stage ovarian cancer who underwent IDS or PDS. The rates of surgical resection and morbidity were reduced after IDS. IDS can be safely used in unresectable advanced-stage ovarian cancer.
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When it comes to treating lipids in patients with heart disease, the mantra may be, The lower the LDL, the better. Data from the multicenter Reversal of Atherosclerosis with Aggressive Lipid Lowering (REVERSAL) trial indicate that aggressive reduction of atherogenic lipoproteins prevents progression of disease.
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In this article, Adams and Nelson integrate results from several disparate fields to advance the concept that autoimmune conditions resemble host vs graft disease and that the graft in many cases may be fetal or maternal cells that lodge in the host, namely the mother or fetus, respectively.
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Changes in screening, endocervical sampling, nomenclature, and improvements in treatment likely explain the increased in situ cervical SCC incidence in white and black women. Increasing AIS incidence over the past 20 years in white women has not yet translated into a decrease in invasive AC incidence.
