Articles Tagged With:
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The Effect of Peripheral Neuropathy in Parkinson’s Disease on Gait and Balance
In this cohort study of 99 patients with Parkinson’s disease (PD), 40% were found to have peripheral neuropathy, with most meeting criteria for small fiber neuropathy. Gait and balance were worse in PD patients with neuropathy compared to those without.
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Do Race and Ethnicity Affect the Likelihood of ICU Admission?
Patients who identify with racial or ethnic minority groups and present with sepsis or acute respiratory failure are more likely to be admitted to the ICU when compared to white patients.
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Does Alcohol Provide Any Health Benefit?
The authors of a large systematic review and meta-analysis concluded there is no health benefit from moderate alcohol intake.
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Does Running Prevent Coronary Artery Disease?
In this cross-sectional review of the Master Athlete Heart study, the authors found lifelong endurance sport participation was not associated with a more favorable coronary plaque composition vs. a healthy lifestyle. Lifelong endurance athletes exhibited more coronary plaques.
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Direct Oral Anticoagulants vs. Warfarin When Treating Renal Dysfunction
A patient-level meta-analysis of five pivotal trials of direct oral anticoagulants (DOACs) vs. warfarin for patients with atrial fibrillation and creatinine clearance levels ranging from normal to 25 mL/min revealed standard-dose DOACs exhibit superior safety and efficacy compared to adjusted-dose warfarin and lower-dose DOACs.
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Valve Replacement Risk and Lifetime Management of Aortic Valve Disease
The authors of an analysis of more than 31,000 patients from the Society of Thoracic Surgeons’ database identified patients undergoing surgical aortic valve replacement (SAVR) after prior transcutaneous AVR (TAVR) or SAVR. SAVR after TAVR raised the risk of mortality vs. SAVR after SAVR.
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Cardiac MRI Predicts Outcomes in Aortic Regurgitation
Cardiac MRI could be used to make management decisions when treating patients living with chronic, asymptomatic aortic regurgitation with preserved left ventricular function, especially when trying to predict severity and possibility of adverse outcomes.
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Age and Sexual Dimorphism in Aortic Regurgitation
Among patients with chronic, significant aortic regurgitation, women and older men without symptoms indicating the need for aortic valve replacement maintained smaller left ventricular volumes than young men and developed adverse clinical events at lower left ventricular volumes.
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Steroids and Pneumonia — So Meta?
In a multicenter, randomized, placebo-controlled trial, hydrocortisone reduced mortality in patients with severe community-acquired pneumonia.
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Adjuvant Systemic Corticosteroid Therapy in Hospitalized Patients with Community-Acquired Pneumonia
This systematic review and meta-analysis of 16 randomized controlled trials (RCTs) studied the use of adjunctive corticosteroid therapy in community-acquired pneumonia. All-cause mortality, intensive care unit admission, and incidence of adverse events were similar in patients who received corticosteroids compared to standard care. However, the corticosteroid therapy group had a lower incidence of progression to mechanical ventilation.