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Pediatric Ethics Consults Adhere to Some — But Not All — National Standards
Core competencies for ethics consultation were established in 2011 by the American Society for Bioethics and Humanities. However, it is unclear if ethics consultants are consistently meeting these standards.
Updated ANA Code of Ethics Reflects Today’s Realities; for Ethicists, it Is Another Tool
Every 10 years, the American Nurses Association updates its Code of Ethics for Nurses. The much-anticipated 2025 changes have important implications for nurses, ethicists, and other healthcare providers.
Infectious Disease Updates
Post-COVID Cryptococcosis — Even in Those Without Immunosuppression; Think Tularemia
RSV Vaccination in Severely Immunocompromised Individuals
The antibody response to respiratory syncytial virus vaccination is significantly impaired in many severely immunocompromised individuals.
Agreeing to Care for Unvaccinated Children
Many primary care clinicians choose not to enroll pediatric patients in their practices when the parents disagree with standard childhood immunization. However, such refusal to provide primary care raises significant controversy and ethical concerns.
A Plasma Cell-Free DNA PCR Panel Test for Invasive Mold Disease
Lieu and colleagues performed a retrospective study of patients with suspected invasive mold disease that showed a high degree of concordance between noninvasive plasma cell-free deoxyribonucleic acid (DNA) polymerase chain reaction (PCR) testing and invasive specimen fungal test results.
Clostridioides difficile Toxin Vaccine Failed to Prevent Primary Infection in Trial
A Phase III randomized clinical trial on adults 50 years of age and older found that a detoxified toxin A/B vaccine failed to reach its primary endpoint of preventing Clostridioides difficile infection. The vaccine was safe and well tolerated.
Uncomplicated Pediatric Appendicitis: Antibiotics or Appendectomy?
Some patients with acute uncomplicated appendicitis do well with initial antibiotic treatment and do not require surgical appendectomy. However, as with adults, approximately one-third of antibiotic-treated children eventually will require surgical removal of the appendix despite the initial short-term success of medical management.
DeWinter T Waves?
The electrocardiogram (ECG) in the figure was obtained from a woman with dyspnea and marked hypertension, but who had no chest pain. How would you interpret this ECG? Should you activate the cath lab?
Nemolizumab-Ilto (Nemluvio)
The U.S. Food and Drug Administration has approved nemolizumab, the first monoclonal antibody specifically targeting the interleukin-31 pathway linked to pruritus and skin inflammation associated with atopic dermatitis.