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Spinal Cord Compression
Diagnosis and management of acute spinal cord compression can be a challenge for the emergency physician. The clinical presentation can range from intermittent, subtle symptoms to acute loss of motor and/or sensory function. Prompt diagnosis and definitive intervention are crucial to preventing long-term neurologic deficit.
Subtle but Real?
The electrocardiogram (ECG) in the figure was obtained from an older man with intermittent chest pain that has awakened him from sleep. How would you interpret this ECG? Should you activate the cath lab?
Suzetrigine Tablets (Journavx)
The U.S. Food and Drug Administration has approved suzetrigine, a first-in-class, non-opioid analgesic, to treat moderate to severe pain.
Treating Hereditary TTR Amyloid Polyneuropathy with Patisiran
A five-year study on patisiran for hereditary transthyretin (TTR) amyloid polyneuropathy found that 65% of patients had stable or improved neuropathy, with better outcomes linked to early treatment. Despite efficacy, 19.4% of patients died. The study underscores the importance of early diagnosis and intervention in managing this progressive disease.
Cardiac and Paracardiac Structure in the SUMMIT Trial
A cardiac magnetic resonance imaging study in a subgroup of the patients in the SUMMIT trial of tirzepatide in patients with heart failure with preserved ejection fraction has demonstrated that patients treated with tirzepatide had reduced left ventricular mass and paracardiac adipose tissue compared to placebo-treated patients, which may partially explain the reduction in heart failure events observed in the main SUMMIT trial.
Magnetic Stimulation and Tai Chi for Older Adults with Sleep Disorders and MCI
This study showed improvement in sleep and cognitive endpoints in patients with sleep disorders and mild cognitive impairment (MCI) treated with a combination of repetitive transcranial magnetic stimulation and tai chi chuan.
RSV Vaccination in Severely Immunocompromised Individuals
The antibody response to respiratory syncytial virus vaccination is significantly impaired in many severely immunocompromised individuals.
Study Shows Increased Interest in New Male Contraceptive Gel
People are interested in a reversible and effective male contraceptive at a time when researchers are closer than ever to making this a reality, studies show.
Preterm Birth Predicts Lower Rate of Desired Permanent Contraception
A new study finds that patients who had preterm delivery were less likely to receive their desired permanent contraception when compared with patients who had at-term delivery.
Cervical Cancer Screening Is Important for All Women — Not Just Unvaccinated
Women who received the human papillomavirus (HPV) vaccine at the youngest age group of 9 to 12 years were less likely to participate in cervical cancer screening (a Pap test) than were those who received the vaccine during their teens and young adulthood, a new study finds.