Articles Tagged With:
-
Prepare Contingency Plans for Transferring Oversight
IRBs should create a contingency plan that would go into effect when a natural disaster or a major problem disrupts operations.
-
Right to Try Law Raises Questions About FDA, IRB Oversight
The FDA “remains committed” to reviewing and approving investigational drugs through its expanded access program, which will continue in conjunction with the recently enacted federal Right to Try law.
-
Prodromal Symptoms Predict the Onset of α-Synucleinopathies
In this review of the common prodromal symptoms of α-synucleinopathies, such as Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy, the authors provided a potential framework for a timeline of the development of these conditions, starting with these prodromal symptoms.
-
Chemotherapy-induced Neuropathy in Childhood Cancer Survivors
Long-term symptoms and disability from chemotherapy-induced peripheral neuropathy occur in more than half of childhood survivors of cancer, with vinca alkaloids and platinum agents implicated most often.
-
Cannabidiol: Does It Help in Drug-resistant Epileptic Encephalopathies?
In this double-blind, placebo-controlled trial, the authors investigated the efficacy of adjunctive cannabidiol in a population of severe developmental epileptic encephalopathies and found some efficacy.
-
Ufmylation and Brain Development: Effects of Gene Mutations
Genetic mutations that can modify post-translational proteins and their interactions may result in serious developmental disorders of the brain. Ufmylation is such a process, and mutations in the genes that regulate this process may have profound effects on the developing brain.
-
Predicting the Risk of Late-onset Alzheimer’s Disease and Dementia Based on Common Genetic Variants
Using a genetic risk score of 23 common genetic variants and apolipoprotein E genotype could help stratify individuals into those very likely to those very unlikely to develop late-onset Alzheimer’s disease and dementia.
-
Ethical Response Needed if Patient Revokes Consent Due to Complications
A new paper explores ethical considerations if patients consent to a treatment plan with the understanding that it carries risks of complications, then revoke consent when complications arise.
-
Study: Older Adults Living Alone With Cognitive Impairment Lack Support
There is a dearth of programs to support older adults living alone with cognitive impairment, creating a need for novel programs and interventions, found a recent study.
-
FDA Addresses Drug Shortages
Detailed annual report to Congress outlines how the agency is handling these concerns.