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In this issue: Statins and liver function; dosing timing for thyroxine; rivaroxaban for VTE, DVT, and stroke; echinacea and the common cold; and FDA actions.
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As reported here in 2003, the World Bank began funding a project to train giant pouched Gambian rats to sniff out tuberculosis (TB) in sputum specimens in sub-Saharan Africa. Rats have been successfully trained to target landmines, and using a similar training/reward technique, pilot data suggested that rats could be trained to detect TB in respiratory specimens.
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Two cases were reported in this paper. the first case was a 52-year-old wildlife biologist who went deer hunting in Virginia in November 2008.
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Patients hospitalized with depression may need extra help understanding the informed consent process for research, due to cognitive impairments that affect their ability to understand information being given to them about a study.
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When a group of researchers set out to study effective ways to screen HMO members for substance abuse problems and to refer them for treatment, they expected that sensitive topic would require strict confidentiality measures.
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IRBs often do a good, or at least adequate, job of maintaining required documentation for studies they review, but there are several key documentation areas in which many IRBs need to improve, according to experts.
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The Office for Human Research Protections (OHRP) has posted its updated and finalized guidance on the IRB continuing review process.
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When and how to release biomarker results is complicated issue for researchers, IRBs
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IRBs can learn a great deal from each other. One research institution's hard-earned lesson and resolution can be another organization's best practices.