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In this issue: Anticholinergic drugs for COPD; pioglitazone for diabetes prevention; insulin degludec in Phase 3 trials; and FDA Actions.
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Admissions to a public hospital in kwazulu-natal, South Africa, for treatment of MDR- and XDR-TB from 2003 to 2008 were examined for health care workers (HCWs) compared with non-HCWs.
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Leptospirosis is a zoonosis caused by multiple serovars of bacteria in the genus Leptospira that are widely distributed in the tropics, as well as some subtropical and temperate areas.
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Herpes zoster vaccine (Zostavax) was licensed in the United States in 2006 subsequent to the publication of the Shingles Prevention Study, a large (n = 38,546) prospective trial that demonstrated a 51% reduction in zoster and a 67% reduction in postherpetic neuralgia in vaccines compared to controls.
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Twice in the past 2 years I've encountered pulmonary histoplasmosis in travelers returning from Central America (Mexico and Costa Rica), and both times the diagnosis proved challenging. One case, in particular, was a 60-year-old man who had traveled to Costa Rica for 1 week and then presented with fever, persistent dry cough, malaise, and complaints of memory loss.
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Flandreau and colleagues at the Hôpital de la Croix-Rousse in Lyon, France, report their experience with patients with chronic neuromuscular disease (CNMD) admitted to their 15-bed medical ICU because of acute respiratory failure (ARF).
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Cardoso and colleagues at University Hospital in Londrina, Brazil, prospectively studied all patients who were admitted to their 17-bed, closed, general adult ICU during a 12-month period.