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In an epidemiologic analysis of SEER data, middle-aged patients with early-stage disease who opted for active surveillance rather than retroperitoneal lymph node dissection experienced a greater rate of second malignancy. The investigators speculate that this may relate to increased radiation exposure (multiple CT scans) and a greater likelihood of subsequent chemotherapy use.
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In a randomized, double-blind, placebo-controlled trial, clonidine and venlafaxine both proved superior to placebo in reducing hot flashes in breast cancer patients. The study was insufficiently powered to prove superiority of one drug over the other. However, venlafaxine produced earlier reductions and it appeared clonidine had more sustained effect (i.e., at 12 weeks of treatment).
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Approximately 2 million children cross internation-al borders each year, and many of them are traveling with older family members to visit friends and relatives (VFR) in the family's country of origin. Previous studies suggest that these children are at particular risk of missing potentially helpful pre-travel interventions and of becoming ill during travel.
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An outbreak of dengue fever in northeastern kenya was first reported in September 2011, and is believed to be spreading rapidly, with at least 5,000 people infected within the first weeks of this outbreak.
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Since the time of the roman empire the animal virus, rinderpest (RPV), German for "cattle plague," has led to countless human deaths from agricultural losses that resulted in famine and disease.
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In this issue: New recommendations for HPV vaccine; guidelines for treatment of essential tremor; updates on smoking cessation drugs; and FDA actions.
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A 40-year-old Gambian male with end-stage renal disease secondary to focal segmental glomerulosclerosis (FSGS) was evaluated for a living unrelated kidney transplant.
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Admission to an ICU increased risk for unintentional medication discontinuation in four of five medication groups commonly used to manage a chronic illness.