Articles Tagged With:
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Predicting Seizure Recurrence with Routine EEG after First Unprovoked Seizure
The authors systematically reviewed prospective and retrospective studies of adults and children undergoing routine electroencephalography (EEG) after a first unprovoked seizure who were followed for at least 1 year. Using positive likelihood ratios, an adult and child with epileptiform discharges on EEG were estimated to have a 77% and 66% probability, respectively, of recurrent seizures.
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Pick Disease: Picking Away at the Pathology
The neuropathologic changes of Pick disease may sequentially progress through the brain in specified phases over time and may correlate with the progression of clinical symptoms.
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Thalamic Pain: Who Is Likely to Develop This Disorder?
In a careful anatomic and physiologic study of patients with thalamic stroke, the authors demonstrated that the combination of anterior pulvinar nucleus involvement with spinothalamic dysfunction predicts a “thalamic pain syndrome” with > 90% sensitivity.
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Peripheral Nerve Disorders After Cardiac Surgery
Following cardiac surgery, about 6% of patients will suffer a peripheral nerve injury, mostly due to compression, traction, or nerve ischemia. Proper patient positioning can prevent most of these injuries.
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Treatment of Acute Ischemic Stroke
MONOGRAPH: The faster definitive stroke treatment is administered, the better the outcomes. Unfortunately, most patients arrive too late.
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IRBs and germline editing research: The outer limits of oversight
Guest columnist J. Benjamin Hurlbut, PhD, discusses human germline editing research and the role IRBs could play in research ethics.
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Human germline gene editing holds great promise, dire possibilities
An international summit on human gene editing recently concluded with a consensus statement to continue basic research in the controversial area, but warned against any clinical trials or human experiments because “once introduced into the human population, genetic alterations would be difficult to remove and would not remain within any single community or country.”
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Using eFeedback helps promote subject safety
Seattle Children’s Research Institute in Seattle found that an eFeedback tool helps the organization improve and ensure the safety of pediatric patients who are enrolled in clinical trials.
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A sample of IRB’s comprehensive training manual
The human research protection office at Washington University in St. Louis has a 43-page training tool that covers general and specific research protection information and tasks for new IRB staff.
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IRBs Train Staff to be Experts
Here's how one human research protection program developed a formal training program that empowered its staff.