Articles Tagged With:
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Case of Terminally Ill Infant Sparks Ethical Debate Over Autonomy
The highly-publicized case of Charlie Gard, a terminally ill British infant, ignited a recent global ethical controversy. The case involved a court battle between the hospital, who wanted to remove the infant from life support, and the child’s parents, who wanted their son transferred to the U.S. for an experimental treatment.
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Capsaicin for Painful Diabetic Peripheral Neuropathy
An 8% capsaicin patch relieves pain and improves sleep in patients with painful diabetic peripheral neuropathy.
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Helping Women at Risk for Breast Cancer to Exercise More and Lose Weight
A web- and phone-based intervention led to significant weight loss and a modest increase in moderate-to-vigorous activity in women at risk of breast cancer.
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High-intensity Interval Training in Older and Younger Adults
High-intensity interval training performed over 12 weeks reversed age-related differences of mitochondrial proteins in adults 65 to 80 years of age, as well as increased insulin sensitivity and VO2 peak, and decreased fat free mass in adults 18 to 30 years of age and 65 to 80 years of age.
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The Great Mimicker: Thyroid Emergencies
Thyroid disease is relatively common, but most often is a benign disease with little clinical significance in the emergency setting. However, even a small insult can disrupt this system and throw the regulation out of control, resulting in the secretion of too much or too little thyroid hormone. Both of these situations can result in the thyroid emergencies thyroid storm and myxedema coma.
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Active Children: Do Higher Levels of Activity Help Prevent Depression?
This prospective study found moderate to vigorous physical activity in early childhood correlated with a decreased number of depressive symptoms in later years.
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Optimizing Electromyography in ALS
In the appropriate clinical setting, electromyography studies of multiple, distal muscle groups in three separate spinal regions showing acute and chronic denervation, are pathognomonic for the diagnosis of amyotrophic lateral sclerosis.
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EEG-based Metrics After Severe Brain Injury
In this cohort study of 104 patients with disorders of consciousness, the authors demonstrated a strong correlation between EEG-based metrics and clinical diagnosis using quantitative behavioral scales, brain metabolism as measured by PET, and clinical outcomes at one year.
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Risk Factors for Seizures in Critically Ill Patients Monitored by Continuous EEG
Investigators prospectively analyzed 72-hour continuous electroencephalograms to identify clinical and electroencephalogram risk factors for having seizures and developed a model for “time-dependent” seizure risk. Electrographic seizures occurred in 23% of all patients. The only significant clinical predictors of seizures were presence of coma and prior clinical seizure history.
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P-syn in Nerve Fibers on Skin Biopsy May Help Diagnose Dementia with Lewy Bodies
This study compared 18 subjects diagnosed with dementia with Lewy bodies (DLB), 23 with nonsynucleinopathy dementia, and 25 healthy controls and demonstrated that phosphorylated alpha-synuclein was found only in the skin nerve fibers of DLB subjects, helping distinguish this type of dementia from other types.