Articles Tagged With:
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Management of Chronic Hypertension in Pregnancy
Chronic hypertension complicates about 5% of pregnancies and has been associated with higher rates of intrauterine growth restriction (IUGR), stillbirth, and, most importantly, superimposed preeclampsia. Although the condition is far from being solved, there have been some major inroads made into its understanding through contemporary investigation.
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The LNG IUS and Stress Reactivity: A Mechanism for Mood Effects or False Signal?
Users of the levonorgestrel (LNG) intrauterine system showed an exaggerated response to stress compared to women using a combined LNG pill or those with natural cycles.
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Just Which Patients Are at Risk of Developing Uterine Fibroids?
Uterine fibroids occur commonly and are the most frequent reason for hysterectomy in the United States. Recognizing the risk factors for developing fibroids can help clinicians identify affected individuals and may lead to new approaches to treatment.
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Brain Reanimation Investigator Reports Dramatic Results
Though the findings come with a considerable caveat — they have yet to be published in a peer-reviewed journal — the lead investigator of a controversial brain reanimation study using “living cadavers” is reporting some dramatic results.
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HHS to Take Action to Protect Research Whistleblowers
The Department of Health and Human Services is taking measures to protect whistleblowers who express concern about human research trials, agreeing with a government watchdog report that the current system has a chilling effect due to “fear of reprisal.”
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IRBs Could Address Ethical Issues Related to Tracking Devices
Some IRBs have begun to review studies that use medical devices with tracking technology. These types of mobile devices raise some ethical and regulatory questions.
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The Choice: A Decision to Decline a Clinical Trial
Ten years ago, Rebecca Dresser, MS, JD, faced a life-changing and, quite possibly, life-saving decision. As a bioethicist and IRB member, she was informed of a diagnosis of cancer and offered a difficult choice: She could enter a new clinical trial for treatment, or follow a specific regimen recommended by oncologists on a tumor board.
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IRB Collaborations With Tech Companies Could Mean What to the IRB?
Tech companies increasingly are partnering with research institutions. These partnerships include sharing data and project collaboration. What IRBs will want to know as this trend continues is what it means from a human research protection perspective.
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Bypassing an IRB Review, Researchers Held Herpes Vaccine Trial on an Island
The human research protection community recently learned of a troubling clinical trial that involved private funding, a U.S. medical college researcher who died this summer, and a study held on a Caribbean island. The clinical trial was for a live attenuated herpes simplex virus-2 vaccine injected in human participants, and it was never reviewed by an IRB.
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Bundled Approach to Handoff Communication Delivers Significant Safety Dividends
With an estimated 80% of the most serious medical errors linked to communication failures, handoff processes are a rich target for improvement. There are numerous tools designed to help providers remember to convey the most important information when transitioning a patient to another provider, but one approach in particular has demonstrated in multiple studies that it can reduce medical errors and preventable adverse events substantially.