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  • Mind the Gap: SHEA Guidance on Ending Isolation

    While there is a dearth of data to make completely informed decisions on aspects of this issue, the Society for Healthcare Epidemiology of America (SHEA) has issued a guidance document that hospitals can use as a framework for making policy.

  • APIC-SHEA Forming Formidable Partnership

    The two major infection control associations in the United States are forging a forward-thinking partnership. It includes several major initiatives that will be enacted this year, with efforts underway to bring in patient and consumer advocates and collaborate in presentations and published papers.

  • A Call to Action to Prevent Non-vent Pneumonia

    What if there were a routine addition to patient care that could save some 10,000 lives annually? An increasing body of research says there is.

  • Flu Vaccine Efficacy Poor as H3N2 Outbreak Surges

    With the nation reeling from an historically bad influenza outbreak, the Centers for Disease Control and Prevention is preparing the public for a dismal efficacy estimate for the 2017-18 vaccine against the predominant H3N2 A flu strain.

  • Stroke Risk in Atrial Fibrillation: A Moving Target?

    An investigation of patients in a national database with atrial fibrillation and no comorbidities and not on aspirin or anticoagulants showed that the clinical features that make up the CHA2DS2-VASc score change over time and can increase a patient’s risk for stroke, which could affect therapy decisions.

  • Physical Activity and Death in CAD Patients

    An observational study of leisure time physical activity (LTPA) assessed at baseline and two years later in stable coronary artery disease patients, who then were followed for about five more years, showed that LTPA at baseline, at two years, and if it went from zero at baseline to some at two years was associated with lower rates of cardiac death compared to inactive patients.

  • Accurately Diagnosing Aortic Dissection

    A prospective study of patients with suspected acute aortic syndromes showed that a clinical risk score plus D-dimer testing carried a positive predictive value of 99.7% and a 0.3% incidence of false-negative studies. The authors recommended that this approach become the standard method for triage to imaging in patients with suspected acute aortic syndromes.

  • What’s the Best Technique to Measure Low-flow, Low-gradient Aortic Stenosis?

    In patients with low-flow, low-gradient aortic stenosis, current guideline-based criteria for identifying true severe aortic stenosis did not predict aortic stenosis severity or survival. Calculation of the projected aortic valve area at a normal transvalvular flow rate more accurately identifies true severe aortic stenosis and is a stronger predictor of outcomes.

  • CASTLE-AF Supports Catheter Ablation for Atrial Fibrillation in Patients with Heart Failure

    Catheter ablation for atrial fibrillation in relatively young men with cardiomyopathy and heart failure is associated with a substantial reduction in arrhythmia burden, improvement in ejection fraction, and reduction in heart failure hospitalizations and mortality compared to medical therapy.

  • Clinical Briefs

    In this section: tackling insomnia with cognitive behavioral therapy; navigating the spurious claims of internet-advertised products; and updated guidelines regarding hypertension treatment.