Articles Tagged With:
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Ethics Services Report Unprecedented Surge in Demand for Consultations
At the same time ethics consultation services are seeing a surge in demand, cases are increasing in complexity.
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A Contemporary Review of Hypertension
Hypertension is a common and serious condition that contributes to an estimated 40% of deaths from coronary heart disease and stroke, and is the second leading cause of end-stage renal disease. Because of the importance and frequency of hypertension in primary care practices, we are devoting two issues to the subject. This issue focuses on the definition of blood pressure and current guidelines, risk factors, relationship to cardiovascular disease, blood pressure measurement, patient evaluation, and secondary causes. The next issue will cover treatments (pharmacological and non-pharmacological), initial therapy, relationship to various disease conditions (diabetes, ischemic heart disease, heart failure, chronic kidney disease, cerebrovascular disease, ischemic stroke, stroke prevention, atrial fibrillation, valvular heart disease, aortic regurgitation, sexual dysfunction), resistant hypertension, hypertensive crises and emergencies, preoperative management, and adherence strategies.
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Untangling the Factors Governing Huntington’s Disease Progression
In a study of more than 3,000 subjects, CAG-repeat-dependent factors affecting age at onset also influenced rates of progression of cognitive, motor, and functional impairments, providing optimism that developing interventions, such as gene silencing therapies, could provide benefit.
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Predicting Future Dementia With Retinal Optical Coherence Tomography
Optical coherence tomography (OCT) is an innovative imaging device that measures thickness of retinal nerve fiber layers and ganglion cells. Thinning of these layers is associated with current and future risk of dementia.
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Use of Amyloid PET Imaging for Diagnosis of Dementia
The use of amyloid positron emission tomography scanning to assist in accurate diagnosis of patients with symptoms of cognitive impairment as well as frank dementia results in a change of diagnosis in at least 25% of patients.
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Viral Therapy for Glioblastoma
In a Phase I/II trial, convection-enhanced delivery of an engineered poliovirus yielded similar median overall survival compared to historical controls. However, a small subgroup of treated patients had extended survival past two years.
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Are Oral Corticosteroids as Effective as Intravenous Steroids in the Treatment of Acute Optic Neuritis?
Based on outcomes measured at one and six months following optic neuritis in the context of multiple sclerosis, these investigators reported similar efficacy when comparing oral to bioequivalent doses of intravenous steroids.
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WHO: Ebola Outbreak in Congo Appears Contained
As of July 1, 2018, the Ebola outbreak in the Democratic Republic of Congo appeared to be ebbing, but infection preventionists should still be wary of cases related to travel. -
Challenges Remain to Reduce C. diff, CAUTIs, and MRSA
The epidemiology of a leading healthcare-associated infection is changing. Clostridium difficile, which kills some 15,000 patients annually, is becoming more of a threat in the community as hard-fought progress is made in hospitals.
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Using PEP or MMR Vaccine for Measles Exposure
During a large community outbreak of measles last year, infection preventionists at Children’s Minnesota Hospital in Minneapolis worked with the state health department to deliver post-exposure prophylaxis (PEP) to 138 (80%) of 173 people who were defined as PEP-eligible.