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Intensive lipid lowering with statin therapy (atorvastatin 80 mg) in patients presenting with acute coronary syndromes (ACS) resulted in improved outcomes compared to treatment with moderate lipid lowering (pravastatin 40 mg) in the PROVE-IT TIMI-22 study (Cannon et al. N Engl J Med. 2004;350:1495-1504), which included patients treated conservatively, as well as those treated with percutaneous coronary intervention (PCI).
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Recurrent peptic ulcer bleeding was increased in patients with known cardiovascular or cerebrovascular disease when daily low-dose aspirin was continued along with proton-pump inhibitors, but overall mortality was significantly less during the 8-week follow-up.
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Fixed dose of IVIg may not be effective in all patients with GBS.
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When ICU practitioners worked under senior clinicians who modeled good hand-hygiene practices, their own behavior with respect to hand hygiene improved.
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In total, 6,771 patients underwent screening for Staphylococcus aureus nasal colonization using real-time polymerase chain reaction (PCR). Of those, 1,251 patients were positive, 917 were enrolled in the trial, and 808 subsequently underwent a surgical procedure. The enrolled patients were treated with nasal mupirocin ointment plus body chlorhexidine baths (or placebo). Rates of S. aureus infection were 3.4% in the mupirocin-chlorhexidine group vs. 7.7% in the placebo group.
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In this issue: Two oral medications for relapsing-remitting MS in phase III development; antihypertensives find new uses; Ginkgo biloba does not prevent cognitive decline in elderly; and FDA Actions.
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Haiti, with a 2007 population of 9.7 million, is the poorest country in the Western Hemisphere, with 55% of households earning less than one $1 U.S. per day. Before the earthquake, 45% of the population lacked access to safe water and 83% lacked access to adequate sanitation.
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Screening for latent TB infection (LTBI) seems to have only gotten that much more complicated and, increasingly, infectious disease experts are being asked to interpret the newer tests results, especially in persons with inflammatory disorders or underlying immune suppression.