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  • Care coordination decreases hospitalizations

    A combination of face-to-face and telephonic case management has resulted in high patient satisfaction ratings and a significant decrease in health care utilization for patients with complex medical needs.
  • Left Main Stenting

    Stenosis of the left main coronary artery has traditionally been an indication for coronary artery bypass graft (CABG) surgery. However, recent studies have shown that percutaneous coronary intervention (PCI) of unprotected left main (ULM) lesions can achieve similar short- and medium-term results to CABG.
  • Clinical Oncology Alert - Full January 2010 Issue in PDF

  • The Importance of Lymph Node Status After Neoadjuvant Therapy for Rectal Cancer

    In a retrospective tumor registry (SEER) analysis of outcomes for rectal-cancer patients treated over a 14-year period with either presurgical or postsurgical radiation therapy, the importance of pathological lymph node status was found to be significantly more adverse for patients who had presurgical treatment. These patients define a subgroup for whom aggressive post-surgical treatment would seem warranted.
  • Pharmacology Watch

    Statin and niacin increase HDL-C, omeprazole reduces effectiveness of clopidogrel, darbe-poetin increases risk of stroke, statins decrease risk of gallstone disease, FDA Actions.
  • Clinical Briefs in Primary Care Supplement

  • Depression and Cancer

    This meta-analysis revealed overall increased mortality of up to 25% in patients experiencing depressive symptoms after cancer diagnosis, and a 39% higher risk in patients diagnosed with major or minor depression after cancer diagnosis, based upon 25 independent studies. Given the low number of studies available to date, the effect of depressive symptoms on cancer recurrence did not reach a level of statistical significance.
  • Physical Activity and Prostate Cancer

    In a large population-based, prospective cohort study, it was found that spending less than 50% of the day in a sedentary position, and increasing amounts of physical activity (e.g., walking or bicycling) appear to be associated with reduced rates of prostate-cancer development.
  • Quality of Life in Long-term Survivors of Hodgkin's Lymphoma

    A long-term longitudinal assessment of quality of life among patients treated for early-stage Hodgkin's lymphoma reveals that, with the exception of fatigue, there is general improvement over time. Factors that influence the rate of improvement include age and sex, but do not include the type of treatment received (radiation vs. chemotherapy).
  • FISH Adequate to Follow CML after Response

    Chromosome banding analysis (CBA) of marrow metaphase cells is the standard method to assess response in CML. The authors compared CBA to interphase fluorescence in situ hybridization (I-FISH) in 664 samples where both methods were performed.