Articles Tagged With:
-
Cholecystokinin as a Biomarker Linking Metabolic Function to Alzheimer’s Disease
In a study cohort from the Alzheimer’s Disease Neuroimaging Initiative, cerebrospinal fluid levels of cholecystokinin were associated with better outcomes that may reflect compensatory protection as Alzheimer’s disease pathology progresses. However, because of significant study limitations, these findings need to be validated in additional studies.
-
Lacosamide for Painful Small Fiber Neuropathy Due to Voltage-Gated Sodium Channel Mutations
The results of this randomized trial showed significant neuropathic pain score reduction with the use of lacosamide in patients with Nav1.7 mutations.
-
Measurement of Brain Vital Signs in Concussed Athletes
These investigators prospectively studied auditory event-related potentials (ERPs) in junior competitive male ice hockey players and identified a pattern of ERPs that distinguishes acutely concussed from non-concussed players, establishing this noninvasive, easy-to-administer test as a biomarker to assist trainers, coaches, and clinicians with making the diagnosis of concussion.
-
Complex Research Ethics Question? Consultants Offer Their Expertise
A research ethics consultation serves as a resource to help answer investigators’ ethical questions.
-
Study Investigates Reasons Why People Do Not Enroll in Clinical Trials
The study found that a main reason why so few people participate is because there is no trial for more than half of cancer patients for their particular type and stage of cancer.
-
Expedited Review Worksheet Includes 111-Criteria Checklist
The IRB at Central Michigan University revised its IRB application to make it more efficient and more closely aligned with federal regulations under 45 CFR § 46.111.
-
Remember IRB Review Criteria When Updating Application Design
A revised application served as an educational tool for researchers, and it helped reviewers focus on the 111 criteria and avoid bringing extraneous questions into their review.
-
New CDC TB Guidelines Will Emphasize Blood Tests
Workflow may get a little smoother for infection preventionists who also wear an occupational health hat. The CDC is expected to soon issue new tuberculosis testing guidelines for healthcare workers that will end routine annual TB screening in favor of a baseline test on hire and retesting after an occupational exposure. -
IPs Prepare for Ebola as Outbreak in Africa Continues
As an Ebola outbreak continues in the Democratic Republic of Congo, infection preventionists again face the threat of an ill traveler from the region walking through the doors of their EDs. -
Central and Local IRBs: Can This Marriage Be Saved?
As the new normal becomes single IRB review for multisite studies, some researchers are wary that this system may undermine the vital role of local IRBs to protect research subjects in their community.