Articles Tagged With:
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Statin Use with Daptomycin: Do We Finally Have a Definitive Answer?
A meta-analysis on published literature and a disproportionality analysis using Food and Drug Administration data found that statin use was associated with the occurrence of daptomycin-induced musculoskeletal adverse events. In most cases, statin use should be discontinued while patients are on daptomycin.
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Salmonella Gastroenteritis — The Risk of a Rapid, Accurate Diagnosis
Availability of molecular testing panel results that were positive for Salmonella in children led to increased hospital admissions, increased subsequent microbiologic testing, and increased antibiotic use — all without benefit to patients.
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Resistance of SARS-CoV-2 Variants to Monoclonal Antibodies
Prevalent SARS-CoV-2 variants are increasingly resistant to therapeutic and prophylactic monoclonal antibodies but remain susceptible to Paxlovid, remdesivir, and molnupiravir.
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When More Is Not Better: Treatment of Prosthetic Valve Endocarditis Due to Staphylococci
Clear evidence of benefit from adjunctive administration a β-lactam and/or a glycopeptide in the treatment of prosthetic valve endocarditis due to staphylococci is lacking. Current guidelines need to be reassessed.
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Vaccination Against Mpox: Does it Work? Is it Safe?
Vaccination, either subcutaneously or intradermally, with the non-replicating JYNNEOS vaccine is safe and effective.
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The Dental Procedure-Infective Endocarditis Link Controversy Continues
Infective endocarditis was more common with dental surgery or tooth extractions in the preceding four weeks in high-risk patients. Researchers abrogated this risk with antibiotic prophylaxis before the procedure.
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Infectious Disease Alert Updates
Loss of Monoclonal Therapy for COVID-19; Cost-Savings of Outpatient Antimicrobial Therapy
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A Review of Insulin Transition
Diabetes mellitus is a collection of chronic metabolic diseases that occur either as the result of insulin deficiency or insulin resistance. One of the primary goals in diabetes treatment includes lowering blood glucose levels sufficiently to prevent microvascular and macrovascular complications. The type of insulin prescribed depends on multiple factors, and insulins frequently are interchanged. Before choosing or transitioning to an appropriate insulin, consider all social determinants and individualize the treatment regimen as “one size does not fit all.”
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Several Groups ‘Deeply Concerned’ About AHRQ’s ED Diagnostics Report
Frontline providers take issue with references cited and data interpretation, among other problems.
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SAMHSA Seeks Opioid Treatment Program Expansion
Under a proposed rule change, the agency wants to tear down more barriers to addiction treatment.