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  • Second Anniversary of Dobbs Decision Shows Vastly Different World for Pregnant Americans

    The two years following the U.S. Supreme Court’s decision to overturn Roe v. Wade and women’s right to privacy in their most intimate healthcare decisions have created an entirely different landscape for people capable of pregnancy in America.

  • Which Is the Key Lead?

    The patient whose ECG appears in the figure is a middle-aged man who presented to the emergency department with new chest pain. Should the cath lab be activated?

  • Cefepime and Enmetazobactam Injection (Exblifep)

    The U.S. Food and Drug Administration has approved the combination of cefepime and enmetazobactam (FPE) for the treatment of complicated urinary tract infections. Cefepime-enmetazobactam was granted a priority review and a five-year marketing exclusivity as part of the Generating Antibiotic Incentive Now (GAIN) Act incentivizing development of new anti-infectives. FPE is distributed by Allecra Therapeutics SAS as Exblifep.

  • Comparing Early vs. Late-Onset MS

    A recent retrospective study, combining data from a United Kingdom patient registry with a United Kingdom neuropathology tissue bank, showed that late-onset multiple sclerosis (MS), referring to disease onset after age 50 years, is linked with increased disability and quicker progression compared to MS onset at a younger age, and has distinct pathological features.

  • Timing of Biomarker Changes in Alzheimer’s Disease

    In a longitudinal multicenter, nested case-control study of cognitive normal participants from China, the time courses of key Alzheimer’s disease biomarkers were identified during the 20 years preceding clinical diagnosis of sporadic Alzheimer’s disease.

  • Better Outcomes for Acute Stroke Patients Who Arrive Rapidly at Endovascular-Capable Centers

    The SELECT2 trial was structured to identify which patients with large ischemic strokes would benefit from endovascular thrombectomy and analyzed the effect of direct arrival at a thrombectomy-capable center compared to transfer from a primary stroke center.

  • Meningococcal Disease Is on the Rise

    The number of cases of infection with Neisseria meningitidis is increasing in the United States. The majority of presentations are with bacteremia; meningitis is infrequent.

  • Fat May Be the Healthiest Part of Dairy

    There are numerous health benefits of dairy fat intake and dairy fat lacks the problems associated with dairy sugar and proteins.

  • Ketamine: Old Drug, New Uses

    Ketamine is a dissociative medication, the only one in its class. Most commonly used as a general anesthetic, it permits patients to tolerate acutely uncomfortable procedures while maintaining most brainstem function, such as breathing and perfusion.

  • Walking at Work: A Helping Hand for a Healthier Heart

    A large prospective cohort study demonstrated that prolonged sitting at work increases the risk for all-cause and cardiovascular disease mortality, but even short periods of physical activity throughout the day may help mitigate the negative effects.