Articles Tagged With:
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No ROMP in the Park: The Complex Intersection Between QI and Clinical Research
Somewhere between typical human research and clinical practice, there is gray area assigned the acronym ROMP — “research on medical practices” — that includes activities such as continuous quality improvement, comparative effectiveness research, and electronic medical record review, the authors of a new study explain.
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A Fresh Method to Adverse Event Tracking in Behavioral Studies
Researchers in Texas studied a state-of-the-art adverse event monitoring program for behavioral health clinical trials.
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Another Good Reason to Consider Early Ablation for Ventricular Tachycardia
In a retrospective cohort of patients with structural heart disease and ventricular tachycardia, amiodarone often could be safely reduced or discontinued after ablation.
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Uncertainties in Assessing Stroke Risk in Atrial Fibrillation
An analysis of 34 randomized trials in atrial fibrillation patients not on anti-coagulation showed considerable variation in stroke rates corresponding to their predicted risk by the CHA2DS2-VASc scores. When these scores are 2 or less, stroke rates are low enough to question the benefit versus risk of anti-coagulation therapy.
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Study Challenges Orthodoxy of IV Hydration for Prevention of Contrast Nephropathy
This trial randomized 660 patients with chronic kidney disease and a planned procedure requiring intravascular iodinated contrast to prophylactic hydration or to no hydration. No hydration was found to be non-inferior for prevention of contrast-induced nephropathy and saved significant costs.
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Diastolic Stress Testing Improves Diagnostic Accuracy in Evaluation of Heart Failure With Preserved Ejection Fraction
Adding echocardiographic assessment of diastolic function during exercise improves the accuracy of current algorithms for evaluating suspected heart failure with preserved ejection fraction.
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Left Ventricular Diastolic Function in the Elderly
Analysis of the ability of echo Doppler measures of diastolic function to predict heart failure and death in community subjects > 65 years of age was improved by applying age-adjusted normal values for e’, which are considerably lower than those recommended in the American Society of Echocardiography guidelines.
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Surviving Sepsis Campaign Guidelines Bundle: Studying How Improved Compliance Might Affect Outcomes
Improved compliance with the Surviving Sepsis Campaign guidelines bundle was associated with a non-statistically significant decrease in the in-hospital mortality of severe sepsis patients.
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The ABCs of In-hospital Cardiac Arrest
In this large, propensity-matched cohort study of patients who experienced an in-hospital cardiac arrest, patients who underwent endotracheal intubation had worse survival to hospital discharge than patients who were not intubated.
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The Clinical Utility of Measuring Dead Space Ventilation in Critical Illness
Here are some of the technologic and physiologic aspects of capnography as they relate to dead space ventilation and their application in the management of critically ill patients.