Articles Tagged With:
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How Case Managers Can Help Patients Reduce Heat Risk
Extreme heat events can become cluster death events. Case managers and health systems can help their patients — especially older patients with heart and/or lung disease — to prevent heat illness.
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Climate Change Could Be Newest Social Determinant of Health
Extreme heat events cause tens of thousands of hospitalizations and ED visits each year. Heat is particularly dangerous for older adults and patients with heart and lung illnesses. Case managers and hospitals can help prevent heat exhaustion by educating at-risk clients about how to stay cool and recognize symptoms.
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Early Communication Can Establish Goals of Care Boundaries
When clinicians initiate the conversation, there can be a better understanding about the wishes of seriously ill patients.
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Involvement of the Peripheral Nervous System in Neurolymphomatosis
Lymphoma that presents with peripheral neuropathy is a challenging diagnosis. Diagnosis and treatment often are delayed, but they can be facilitated by early consideration and imaging with fluorodeoxyglucose-positron emission tomography. Early diagnosis and hematologic treatment may be effective.
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Somatic Variants in Ras/Raf/MAPK Pathway Play a Role in Mesial Temporal Lobe Epilepsy
Eleven somatic variants enriched in the hippocampus were detected in a group of patients with drug-resistant mesial temporal lobe epilepsy (MTLE). Most somatic variants are mutations in the Ras/Raf/mitogen-activated protein kinase (MAPK) pathway. Overactivation of the Ras/Raf/MAPK pathway was detected in MTLE with somatic variants.
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Trichloroethylene Exposure Has Been Linked to an Increased Risk of Parkinson’s Disease
Preliminary evidence suggests trichloroethylene is a potential environmental risk factor for Parkinson’s disease. Further research is needed to confirm this association.
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Lovastatin for Reducing Risk and Delaying Onset of ALS
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease without available treatments that significantly alter the disease course. Using Medicare databases and pharmacy records, with multiple logistic regression models, researchers studied three candidate drugs (lovastatin, sulfasalazine, and telmisartan) that were identified as possible therapies for ALS and their effects on SOD1G93A transgenic mice. Animal testing showed a delay in disease onset and prolonged survival in mice treated with a mouse-equivalent dose of lovastatin 40 mg, but showed no benefit from the other two candidate drugs.
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A Primer on Excessive Daytime Sleepiness and Narcolepsy
Many new drugs are coming on the market to treat daytime sleepiness, as well as insomnia, as the prevalence of sleep disorders continues to grow in modern society. Neurologists should familiarize themselves with these disorders and the various ways to treat them safely.
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Pre-Conception Hepatitis B and Congenital Heart Disease
A new study suggests that both women and men who have had hepatitis B infection prior to conceiving offspring are more likely to give birth to children with congenital heart disease.
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Inappropriate Antibiotic Prescribing Is Common for Elective Surgeries
A retrospective cohort study of adults who underwent an elective craniotomy, hip replacement, knee replacement, spinal procedure, or hernia repair revealed only 59% adhered to recommended guidelines on prophylactic antibiotic prescribing. Unnecessary vancomycin use was the most common reason for nonadherence and had 19 times higher risk for acute kidney injury.