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  • For Older Patients, Loneliness Might Be Biggest Social Determinant of Health

    Loneliness and social exclusion can have a big impact on patients’ health and quality of life, and it is a problem that is compounded by deteriorating health as people grow older.

  • Does Every Woman Deserve a High-volume Gynecologic Surgeon?

    Generally, gynecologic surgical complications are higher with lower-volume surgeons.

  • Vaginal Progesterone vs. Cerclage to Prevent Preterm Birth

    SYNOPSIS: A recent indirect comparison meta-analysis has shown that vaginal progesterone is as useful in decreasing preterm birth and its associated adverse outcomes as cervical cerclage in patients with a history of preterm birth and short cervices.

  • Intrauterine Devices and Cervical Cancer

    In this case-control study, levonorgestrel IUD use was associated with a slightly increased rate of CIN 2 but not CIN 3. Copper IUD use was not associated with CIN 2 or CIN 3.

  • Primary HPV Screening: Ready for Prime Time?

    In this randomized, controlled trial of more than 25,000 women, participants with negative high-risk human papillomavirus testing at baseline had rates of CIN 3+ at 48 months that were lower compared to negative liquid-based cytology testing.

  • USPSTF Recommendation: Screening for Cervical Cancer

    The U.S. Preventive Services Task Force (USPSTF) recently updated its recommendations for cervical cancer screening. Practitioners currently following guidelines published by ASCCP (and supported by ACOG) will not find any discrepancies in the new USPSTF position

  • What Is Really BRUEing?

    In May 2016, the American Academy of Pediatrics (AAP) published clinical practice guidelines titled Brief Resolved Unexplained Events (Formerly Apparent Life-Threatening Events) and Evaluation of Lower-Risk Infants, suggesting a new termi­nology, an evaluation based on the risk of recur­rent events or serious underlying causes, and key action statements (management recommendations) for patients meet­ing the brief resolved unexplained events (BRUE) definition for lower-risk patients. The authors review and discuss the definitions and key management strategies recommended in these new guidelines.

  • Metabolic Acidosis in the ICU

    Sodium bicarbonate therapy for severe metabolic acidemia did not affect a primary composite outcome of all-cause mortality at 28 days and at least one organ failure at day 7. However, in an a priori-defined stratum of patients with acute kidney injury, sodium bicarbonate therapy decreased 28-day mortality and the primary outcome.

  • Severe Sepsis and Septic Shock Early Management Bundle

    When the Severe Sepsis and Septic Shock Early Management Bundle was used to identify patients with severe sepsis or patients in septic shock, delays in lactate measurements for patients with abnormal lactate levels were associated with delayed initiation of antibiotic therapy and increased mortality.

  • Should We Use Early Physical Therapy for Respiratory Muscles?

    Mechanically ventilated patients undergoing inspiratory muscle training demonstrated significant increases in both maximum inspiratory and expiratory muscle pressures; the training was associated with reduced weaning duration of 2.3 days.