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Cidofovir (CDV), which was licensed in the United States in 1996 for the treatment of cytomegalovirus retinitis, has been used successfully in a number of other viral infections, including those due to drug-resistant herpes simplex, varicella-zoster, and adenovirus.
Anaerobes were not found to play an important role in the etiology of pneumonia in nursing home residents with an increased risk of aspiration.
Organisms that may only be isolated by using coculture with amoeba and that are present in hospital water supplies may be implicated in some cases of ventilator-associated pneumonia.
Neither adding a single dose of ceftriaxone to a 10-day course of doxycycline nor extending the duration of doxycycline therapy to 20 days is better than a straightforward 10-day course of oral doxycycline in the treatment of patients with erythema migrans.