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In this large, retrospective cohort study, women with a history of bariatric surgery were at a small increased risk of both spontaneous and medically indicated preterm birth and small for gestational age births.
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Hopefully, as multi-institution, randomized trials are developed for second-line treatment of pancreatic cancer, CA19-9 levels will be included both pre- and post-first cycle treatment and responses compared with the established RECIST criteria.
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Calculating 60-day mortality risk by these readily available parameters (ECOG PS and WBC) can be used to identify high-risk patients who may require heightened surveillance after standard or experimental chemotherapy or, alternatively, a reduction in treatment intensity.
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It is indeed ironic that 16 years after the landmark Burris study, innovations in pancreatic cancer treatment still lack essential quality-of-life data.
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This paper represents the largest collection of cases with central path review and provides better clarity to prognostic factors previously intimated from retrospective work.
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As this issue went to press, the Centers for Disease Control and Prevention issued a health advisory notice to public health officials and clinicians on recognizing, managing, and reporting chikungunya virus infections in travelers returning from the Caribbean.
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Many more cases of Lyme carditis may go unrecognized
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In a prospective, open-label, intervention study conducted over four influenza seasons, higher dose oseltamivir compared to standard dose produced no additional benefits in patients with influenza A infection.