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Episodes of severe sepsis in older adults is associated with worsening cognition and functional status.Source: Iwashyna TJ, et al. Long-term cognitive impairment and functional disability among survivors of severe sepsis. JAMA 2010;304:1787-94.
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A 74-year retired veterinarian presents to the emergency department (ED) with shortness of breath. He was recently diagnosed with diffuse large-cell lymphoma with prominent abdominal lymphadenopathy and positive bone marrow and has been treated with two cycles of R-CHOP.
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In a multicenter study, critically ill patients with initial hyperlactatemia had improved outcomes (including shorter ICU stays and lower adjusted mortality) compared to control patients when they were managed for the first 8 hours with a resuscitation protocol targeted at reducing the lactate level by at least 20% every 2 hours.
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The relationship between blood pressure and cardiovascular events remains controversial, especially in patients with coronary artery disease who may need increased pressures to have adequate myocardial perfusion.
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Gastrointestinal (GI) bleeding is a major complication of dual anti-platelet therapy (DAPT) with aspirin and clopidogrel.
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In the H1N1 influenza A pandemic, many infected health care workers failed to wear personal protective equipment. They became sick after caring for infected patients. In addition, they were infected after socializing with co-workers who came to work sick.
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On December 11, 2009, the California Department of Public Health (CDPH) began an investigation into two secondary cases of meningococcal disease following occupational exposure to an unconscious adult.
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In areas of limited maternal care across Africa, obstructed labor leads to stillbirth and necrosis of maternal tissues.