A drug has been approved to treat high plasma levels of methotrexate. Glucarpidase is a bacterial enzyme produced by recombinant DNA technology using genetically modified Exherichia coli. Glucarpidase is a carboxypeptidase enzyme that metabolizes methotrexate to its inactive metabolites. It is marketed by BTG International Inc. as Voraxaze.
A drug has been approved to treat high plasma levels of methotrexate. Glucarpidase is a bacterial enzyme produced by recombinant DNA technology using genetically modified Exherichia coli. Glucarpidase is a carboxypeptidase enzyme that metabolizes methotrexate to its inactive metabolites. It is marketed by BTG International Inc. as Voraxaze.
Glucarpidase for Injection (Voraxaze®)
February 15, 2012