Here are criteria for GP IIb/IIIa inhibitors
The following are indications and contraindications for glycoprotein IIb/IIIa inhibitors:
Indications:
1. For the treatment of patients with acute coronary syndrome (Unstable Angina with Non-Q- Wave Myocardial Infarction) with chest pain more than 10 minutes in duration within 24 hours of presentation, with at least one of the following findings:
• Electrocardiogram changes showing: ST depression >0.5 mm, ST elevation between 0.6 mm and 1 mm, or T-wave inversion > 1.0 mm.
• Elevated cardiac enzymes, isoenzyme of creatine kinase with muscle and brain subunits, or troponin.
2. Patients undergoing percutaneous coronary intervention.
Contraindications:
1. A history of bleeding diathesis, or active abnormal bleeding within the previous 30 days.
2. Uncontrolled severe hypertension: systolic > 200 mm/hg, or diastolic > 110 mm/hg.
3. Major surgery within six weeks.
4. History of stroke within 30 days, or any history of hemorrhagic stroke.
5. Platelet count < 100,000.
6. Dependence on renal dialysis.
7. For patients with a serum creatinine > 2, the dosage should be reduced per prescribing recommendations.
8. Assess patient for warfarin and/or excessive nonsteroidal anti-inflammatory drug usage.
Source: St. Jude Medical Center, Fullerton, CA.
Subscribe Now for Access
You have reached your article limit for the month. We hope you found our articles both enjoyable and insightful. For information on new subscriptions, product trials, alternative billing arrangements or group and site discounts please call 800-688-2421. We look forward to having you as a long-term member of the Relias Media community.