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SSRIs increase the risk of upper gastrointestinal bleeding, and this effect is potentiated by concomitant NSAID or aspirin use.

Use of Selective Serotonin Reuptake Inhibitors and Risk of Upper Gastro-intestinal Tract Bleeding

SSRIs increase the risk of upper gastrointestinal bleeding, and this effect is potentiated by concomitant NSAID or aspirin use.