Murderers’ Row: Resistant to Drugs, Threats to Humans
Projected increase over next decade part of pathogen assessments
In a recently published report on antibiotic threats in the United States, the Centers for Disease Control and Prevention (CDC) classified pathogens as urgent, serious, concerning, or put them on a “watch list.”1
The pathogens were assessed and categorized according to factors that include the following:
• Clinical effect
• Economic effect
• Incidence
• 10-year projection of incidence
• Transmissibility
• Availability of effective antibiotics
• Barriers to prevention
“The assessment focused on domestic impact, but the international context of antibiotic resistance was taken into account in the 10-year incidence projection,” the CDC noted. “Threats assigned to the urgent and serious categories require greater attention and action.”
Urgent Threats
• Carbapenem-resistant Acinetobacter
• Candida auris
• Clostridioides difficile
• Carbapenem-resistant Enterobacteriaceae (CRE)
• Drug-resistant Neisseria gonorrhoeae
Serious Threats
• Drug-resistant Campylobacter
• Drug-resistant Candida
• Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae
• Vancomycin-resistant Enterococci (VRE)
• Multidrug-resistant Pseudomonas aeruginosa
• Drug-resistant nontyphoidal Salmonella
• Drug-resistant Salmonella serotype Typhi
• Drug-resistant Shigella
• Methicillin-resistant Staphylococcus aureus (MRSA)
• Drug-resistant Streptococcus pneumoniae
• Drug-resistant Tuberculosis
Concerning Threats
• Erythromycin-resistant group A Streptococcus
• Clindamycin-resistant group B Streptococcus
Watch List
• Azole-resistant Aspergillus fumigatus
• Drug-resistant Mycoplasma genitalium
• Drug-resistant Bordetella pertussis
REFERENCE
- Centers for Disease Control and Prevention. Antibiotic resistance threats in the United States 2019. Available at: https://bit.ly/2roWiaO. Accessed Dec. 9, 2019.
In a recently published report on antibiotic threats in the United States, the Centers for Disease Control and Prevention classified pathogens as urgent, serious, concerning, or put them on a “watch list.”
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