Non-β-hemolytic streptococci (NBHS) are the most common cause of infective endocarditis. In this retrospective study of 399 patients with NBHS bacteremia, 26 patients had endocarditis. HANDOC score (heart murmur, aetiology by specific species of NBHS, number of positive blood cultures, duration of symptoms, only one species in blood culture, and community-acquired infection) was predictive of endocarditis vs. non-endocarditis bacteremia.
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