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<p>Increasingly, payers require patients to try and fail “first-line” treatments before payers approve more costly treatments. Include supporting articles from the literature supporting off-label use, and ask physicians to supply statements on why the first-line therapy is not appropriate.</p>

Payers Want Evidence That Patient Already Tried First-line Therapy

Keep patient access ‘as transparent as possible’

Increasingly, payers require patients to try and fail “first-line” treatments before payers approve more costly treatments. Include supporting articles from the literature supporting off-label use, and ask physicians to supply statements on why the first-line therapy is not appropriate.