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Cyclooxygenase 2 (COX 2) inhibitors may not be as safe as previously thought. These agents have a considerable risk of adverse gastrointestinal events. The concurrent use of ulcer-healing drugs appears to decrease this risk.

Is it Better to Prescribe a Cyclooxygenase-2 Inhibitor or Conventional NSAIDs to Prevent Adverse Gastrointestinal Events?

January 15, 2006

Cyclooxygenase 2 (COX 2) inhibitors may not be as safe as previously thought. These agents have a considerable risk of adverse gastrointestinal events. The concurrent use of ulcer-healing drugs appears to decrease this risk.