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The oral absorption and clearance of either amoxicillin or cefaclor was tested in women who also ingested cranberry juice cocktail. Although there was modest slowing of absorption (amoxicillin and cefaclor) and decreased maximum serum drug concentration (cefaclor) when the cranberry groups were compared to control groups (water), the overall clinical effect seemed to be negligible.

Cranberry Juice Cocktail and Two Antibiotics

The oral absorption and clearance of either amoxicillin or cefaclor was tested in women who also ingested cranberry juice cocktail. Although there was modest slowing of absorption (amoxicillin and cefaclor) and decreased maximum serum drug concentration (cefaclor) when the cranberry groups were compared to control groups (water), the overall clinical effect seemed to be negligible.