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In a large series of MGUS patients followed prospectively, transformation to multiple myeloma or other hematological malignancy, although present, was at a rate considerably lower than expected, based upon reports from retrospective series. Nevertheless, overall survival for MGUS patients was significantly less than that for the general population.

Monoclonal Gammopathy: Not So Benign

February 1, 2009

In a large series of MGUS patients followed prospectively, transformation to multiple myeloma or other hematological malignancy, although present, was at a rate considerably lower than expected, based upon reports from retrospective series. Nevertheless, overall survival for MGUS patients was significantly less than that for the general population.

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